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Circulating CD4+ memory T cells give rise to a CD69+ resident memory T cell population in non-inflamed human skin

2018-12-09

Abstract excerpt

The blood of human adults contains a pool of circulating CD4+ memory T cells and normal human skin contains a CD4+CD69+ memory T cell population that produce IL17 in response to Candida albicans. Here we studied the generation of CD4+CD69+ memory T cells in human skin from a pool of circulating CD4+ memory T cells. Using adoptive transfer of human PBMC into a skin-humanized mouse model we discovered the generation...

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Literature Corpus work
bed045cb-0517-5f2c-b373-ecd035e25254
DOI
10.1101/490094
Open publication

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Circulating CD4+ memory T cells give rise to a CD69+ resident memory T cell population in non-inflamed human skinDOI 10.1101/490094
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