Memory regulatory T cells reside in human skin.

doi:10.1172/JCI72932

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Memory regulatory T cells reside in human skin.

The Journal of clinical investigation - 1 Mar 2014

Sanchez Rodriguez Robert, Pauli Mariela L, Neuhaus Isaac M, Yu Siegrid S, Arron Sarah T, Harris Hobart W, Yang Sara Hsin-Yi, Anthony Bryan A, Sverdrup Francis M, Krow-Lucal Elisabeth, MacKenzie Tippi C, Johnson David S, Meyer Everett H, Löhr Andrea, Hsu Andro, Koo John, Liao Wilson, Gupta Rishu, Debbaneh Maya G, Butler Daniel, Huynh Monica, Levin Ethan C, Leon Argentina, Hoffman William Y, McGrath Mary H, Alvarado Michael D, Ludwig Connor H, Truong Hong-An, Maurano Megan M, Gratz Iris K, Abbas Abul K, Rosenblum Michael D

Abstract excerpt

Regulatory T cells (Tregs), which are characterized by expression of the transcription factor Foxp3, are a dynamic and heterogeneous population of cells that control immune responses and prevent autoimmunity. We recently identified a subset of Tregs in murine skin with properties typical of memory cells and defined this population as memory Tregs (mTregs). Due to the importance of these cells in regulating tissue...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hair Follicle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunologic Memory

Share to Interleukin-17

Share to Mice, Inbred NOD

Share to Psoriasis

Share to Receptors, Antigen, T-Cell

Share to Receptors, CCR7

Share to T-Lymphocytes, Regulatory

Source

Open in PubMed Open full text

Identifiers

PMID: 24509084
DOI: 10.1172/JCI72932
PMCID: PMC3934172

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Memory regulatory T cells reside in human skin.PMID 24509084Read ↗

Functional heterogeneity of human skin-resident memory T cells in health and disease.Semantic proximity Read ↗

A novel humanized mouse model to study the function of human cutaneous memory T cells <i>in vivo</i> in human skinSemantic proximity Read ↗

Skin-Resident Memory T Cells: Pathogenesis and Implication for the Treatment of PsoriasisSemantic proximity Read ↗

Tissue-resident memory T cells in the skin.Semantic proximity Read ↗

Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells.Semantic proximity Read ↗

Long-term skin-resident memory T cells proliferate in situ and are involved in human graft-versus-host diseaseSemantic proximity Read ↗

Human Regulatory T Cells: Understanding the Role of Tregs in Select Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin CancersSemantic proximity Read ↗

Regulatory T cells in skin.Semantic proximity Read ↗

Inflammatory Memory in Chronic Skin DiseaseSemantic proximity Read ↗

Developing human fetal skin demonstrates a unique lymphocyte signatureSemantic proximity Read ↗

Circulating CD4+ memory T cells give rise to a CD69+ resident memory T cell population in non-inflamed human skinSemantic proximity Read ↗

Antigen-specific expansion of human regulatory T cells as a major tolerance mechanism against mucosal fungi.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.