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Drug Repositioning Based on Single-Cell Transcriptomics Data Identifies Quinidine as a Potential Drug for Treating Osteoporosis

2026-07-15

Abstract excerpt

Osteoporosis (OP) is a systemic skeletal disease characterized by low bone mass and micro-architectural deterioration of bone tissue, but no effective clinical therapies exist. To address this unmet need, we employed a computational pipeline drug repositioning method based on single-cell data and Mendelian randomization analysis to screen potential candidate drugs for the treatment of osteoporosis. Quinidine was i...

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Literature Corpus work
becaea1f-f1a9-5d4c-b199-e488d2e0e798
DOI
10.20944/preprints202607.1150.v1
Open publication

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Drug Repositioning Based on Single-Cell Transcriptomics Data Identifies Quinidine as a Potential Drug for Treating OsteoporosisDOI 10.20944/preprints202607.1150.v1
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