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GPC2 promotes prostate cancer progression via MDK-mediated activation of PI3K/AKT signaling pathway

17 Jul 2024

Abstract excerpt

Prostate cancer is a major medical problem for men worldwide. Advanced prostate cancer is currently incurable. Recently, much attention was paid to the role of GPC2 in the field of oncology. Nevertheless, there have been no investigations of GPC2 and its regulatory mechanism in prostate cancer. Here, we revealed a novel action of GPC2 and a tumor promoting mechanism in prostate cancer. GPC2 was upregulated in...

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PMID: 39014225
DOI: 10.1007/s10142-024-01406-y

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