Article

<i>HOXA9</i> acts as a regulatory switch in acute myeloid leukaemia and myeloproliferative neoplasms

2021-03-06

Abstract excerpt

Blood malignancies arise from the dysregulation of haematopoiesis. The type of blood cell and the specific order of oncogenic events initiating abnormal growth ultimately determine the cancer subtype and subsequent clinical outcome. HOXA9 plays an important role in acute myeloid leukaemia (AML) prognosis by promoting blood cell expansion and altering differentiation; however, the function of HOXA9 in other blood m...

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Literature Corpus work: be325a97-3304-5838-8e8c-04288a301660
DOI: 10.1101/2021.03.05.434116

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