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Article

Risk factors for calcineurin inhibitor nephrotoxicity after renal transplantation: a systematic review and meta-analysis.

Drug design, development and therapy - 1 Jan 2018

Xia Tianyi, Zhu Sang, Wen Yan, Gao Shouhong, Li Mingming, Tao Xia, Zhang Feng, Chen Wansheng

Abstract excerpt

BACKGROUND: Nephrotoxicity of calcineurin inhibitors (CNIs) is the major concern for long-term allograft survival despite its predominant role in current immunosuppressive regime after renal transplantation. CNI nephrotoxicity is multifactorial with demographic, environmental, and pharmacogenetic flexibility, whereas studies indicating risk factors for CNI nephrotoxicity obtained incomplete or conflicting...

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Identifiers

PMID: 29535503
DOI: 10.2147/DDDT.S149340
PMCID: PMC5836651

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