Back to search

Article

Canine Somatic Mutations from Whole Exome Sequencing of B-Cell Lymphomas in Six Canine Breeds

2023-07-12

Abstract excerpt

Canine lymphoma (CL) is one of the most common malignant tumors in dogs. The cause of CL remains unclear. Genetic mutations that have been suggested as possible causes of CL are not fully understood. Whole-exome sequencing (WES) is a time- and cost-effective method for detecting genetic variants targeting only protein-coding regions (exons) that are part of the entire genome region. A total of eight patients with...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
be01f83b-679c-5bff-be9f-831a180c3279
DOI
10.20944/preprints202307.0808.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Canine Somatic Mutations from Whole Exome Sequencing of B-Cell Lymphomas in Six Canine BreedsDOI 10.20944/preprints202307.0808.v1
Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background.Semantic proximity
Consensus-based somatic variant-calling method correlates <i>FBXW7</i> mutations with poor prognosis in canine B-cell lymphomaSemantic proximity
The genomic landscape of canine diffuse large B-cell lymphoma identifies distinct subtypes with clinical and therapeutic implicationsSemantic proximity
Comparative Genomic Analysis of Multiple Mammary Tumors from a Single Dog: Whole-Genome Sequencing StudySemantic proximity
The K9 lymphoma assay allows a genetic subgrouping of canine lymphomas with improved risk classificationSemantic proximity
Expanding the spectrum of canine Diffuse Large B-cell Lymphoma (cDLBCL) genetic aberrations through whole genome sequencing (WGS) analysisSemantic proximity
Mutational landscape of canine B-cell lymphoma profiled at single nucleotide resolution by RNA-seqSemantic proximity
Whole genome sequencing analysis of high confidence variants of B-cell lymphoma in Canis familiaris.Semantic proximity
The K9 lymphoma assay allows a genetic subgrouping of canine lymphomas with improved risk classification.Semantic proximity
Canine tumor mutational burden is correlated with TP53 mutation across tumor types and breeds.Semantic proximity
Characterization of the genomic landscape of canine diffuse large B-cell lymphoma reveals recurrent H3K27M mutations linked to progression-free survival.Semantic proximity
Genomic analysis across 53 canine cancer types reveals novel mutations and high clinical actionability potential.Semantic proximity
Select a neighboring publication to make it the new centre.