Genomic analysis across 53 canine cancer types reveals novel mutations and high clinical actionability potential.

doi:10.1111/vco.12944

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Genomic analysis across 53 canine cancer types reveals novel mutations and high clinical actionability potential.

Veterinary and comparative oncology - 1 Mar 2024

Sakthikumar Sharadha, Warrier Manisha, Whitley Derick, Facista Salvatore, Adkins Jonathan, Aman Sara, Tsinajinnie Darwin, Duran Natalie, Siravegna Giulia, Ahmed Zeeshan, Day Kenneth, Jenkins Brooklyn, Patel Nidhi, Ryden Kirk, Nadai Joe, Banovich Kathryn, Powers Barbara, Edwards Jeffrey, Steinberg Jennifer, Fielder Susan, Wong Shukmei, Byron Sara A, Izatt Tyler, Zismann Victoria, Boateng Martin, Zhu Zhanyang, Chuang Han-Yu, Trent Jeffrey M, Haworth David, Chon Esther, Hendricks William, Wang Guannan

Abstract excerpt

A genomic understanding of the oncogenic processes and individual variability of human cancer has steadily fueled improvement in patient outcomes over the past 20 years. Mutations within tumour tissues are routinely assessed through clinical genomic diagnostic assays by academic and commercial laboratories to facilitate diagnosis, prognosis and effective treatment stratification. The application of genomics has...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cancer Genomics and Diagnostics

Share to Dog Diseases

Share to Veterinary Oncology Research

Source

Open in PubMed

Identifiers

PMID: 38053317
DOI: 10.1111/vco.12944

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic analysis across 53 canine cancer types reveals novel mutations and high clinical actionability potential.PMID 38053317Read ↗

Analyses of canine cancer mutations and treatment outcomes using real-world clinico-genomics data of 2119 dogsSemantic proximity Read ↗

The Genetic Landscape of Canine Tumors: Insights from the Canine Cancer Genome Atlas (CCGA)Semantic proximity Read ↗

Canine Oncopanel: A capture-based, NGS platform for evaluating the mutational landscape and detecting putative driver mutations in canine cancers.Semantic proximity Read ↗

Clinical Use of Molecular Biomarkers in Canine and Feline Oncology: Current and FutureSemantic proximity Read ↗

Canine tumor mutational burden is correlated with TP53 mutation across tumor types and breeds.Semantic proximity Read ↗

The K9 lymphoma assay allows a genetic subgrouping of canine lymphomas with improved risk classificationSemantic proximity Read ↗

Standing in the canine precision medicine knowledge gap: Improving annotation of canine cancer genomic biomarkers through systematic comparative analysis of human cancer mutations in COSMIC.Semantic proximity Read ↗

The shared selection landscape of dog and human cancersSemantic proximity Read ↗

Canine tumor mutation rate is positively correlated with TP53 mutation across cancer types and breedsSemantic proximity Read ↗

Genomic profiling of canine mast cell tumors identifies DNA copy number aberrations associated with KIT mutations and high histological grade.Semantic proximity Read ↗

Comprehensive Analysis of Microsatellite Instability in Canine Cancers: Implications for Comparative Oncology and Personalized Veterinary MedicineSemantic proximity Read ↗

Unraveling the chaotic genomic landscape of primary and metastatic canine appendicular osteosarcoma with current sequencing technologies and bioinformatic approaches.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.