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Article

Whole genome sequencing analysis of high confidence variants of B-cell lymphoma in Canis familiaris.

PloS one - 1 Jan 2020

Sparks Alana, Woods J Paul, Bienzle Dorothee, Wood Geoffrey A, Coomber Brenda Lynn

Abstract excerpt

Lymphoma (lymphosarcoma) is the second most frequent cancer in dogs and is clinically comparable to human non-Hodgkin lymphoma. Factors affecting canine lymphoma progression are unknown and complex, but there is evidence that genetic mutations play an important role. We employed Next Gen DNA sequencing of six dogs with multicentric B-cell lymphoma undergoing CHOP chemotherapy to identify genetic variations...

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Identifiers

PMID: 32857815
DOI: 10.1371/journal.pone.0238183
PMCID: PMC7454977

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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