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Effective Treatment With Endostar and Crizotinib Sequential Alectinib in a Lung Adenocarcinoma Patient With Brain Metastases Harboring a Novel CLHC1/RNT4 Intergenic Region- ALK Fusion

2021-10-27

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Anaplastic lymphoma kinase (<italic>ALK</italic>) fusion, an important driven oncogene mutation, occurrs in 3%~7% non-small cell lung cancers (NSCLC), and <italic>EML4</italic> is the most common partner gene. With the widespread application of next-generation sequencing (NGS), more gene breakpoint fusions have been discovered, and functional fusion transcripts...

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Literature Corpus work
e2d658ca-4784-5ca3-b859-8cd3325de418
DOI
10.21203/rs.3.rs-1008103/v1
Open publication

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