Article

RNetDys: identification of disease-related impaired regulatory interactions due to SNPs

2022-10-11

Abstract excerpt

The dysregulation of regulatory mechanisms due to Single Nucleotide Polymorphisms (SNPs) can lead to diseases and does not affect all cell (sub)types equally. Current approaches to study the impact of SNPs in diseases lack mechanistic insights. Indeed, they do not account for the regulatory landscape to decipher cell (sub)type specific regulatory interactions impaired due to disease-related SNPs. Therefore, charac...

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Literature Corpus work: bdae2157-8496-501a-875e-e0fde4751726
DOI: 10.1101/2022.10.08.511312

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