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Article

Ageing characteristics of bone indicated by transcriptomic and exosomal proteomic analysis of cortical bone cells

10 May 2019

Abstract excerpt

BACKGROUND: Degenerative changes in the skeleton play an important role in ageing. As the foremost sensors and orchestrators of bone remodelling, osteocytes contribute significantly to the health of the skeleton. Embedded in a mineralized bone matrix, the osteocyte network and the surrounding lacunar canaliculae work together as a functional syncytium-the osteocytic lacunar-canalicular system (OLCS). However,...

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PMID: 31077243
DOI: 10.1186/s13018-019-1163-4

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