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Article

The Mechanical Contribution of Vimentin to Cellular Stress Generation.

Journal of biomechanical engineering - 1 Jun 2018

van Loosdregt Inge A E W, Weissenberger Giulia, van Maris Marc P F H L, Oomens Cees W J, Loerakker Sandra, Stassen Oscar M J A, Bouten Carlijn V C

Abstract excerpt

Contractile stress generation by adherent cells is largely determined by the interplay of forces within their cytoskeleton. It is known that actin stress fibers, connected to focal adhesions, provide contractile stress generation, while microtubules and intermediate filaments provide cells compressive stiffness. Recent studies have shown the importance of the interplay between the stress fibers and the...

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PMID: 29450503
DOI: 10.1115/1.4039308

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