Article

Retinal aging transcriptome and cellular landscape in association with the progression of age-related macular degeneration

2022-04-04

Abstract excerpt

Age is the main risk factor for age-related macular degeneration (AMD), a leading cause of blindness in the elderly, with limited therapeutic options. Here we systematically analyzed the transcriptomic characteristics and cellular landscape of the aging retina from controls and patients with AMD. We identify the aging genes in the retina that are associated with innate immune response and inflammation. Deconvoluti...

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Literature Corpus work: bd513755-6e23-5930-a620-5f4bbd41029f
DOI: 10.1101/2022.04.03.22273375

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