Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Retinal Aging Transcriptome and Cellular Landscape in Association With the Progression of Age-Related Macular Degeneration

26 Apr 2023

Abstract excerpt

Purpose: Age is the main risk factor for age-related macular degeneration (AMD), a leading cause of blindness in the elderly, with limited therapeutic options. Methods: Here, we analyze the transcriptomic characteristics and cellular landscape of the aging retinas from controls and patients with AMD. Results: We identify the aging genes in the neural retina, which are associated with innate immune response and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ophthalmology and Visual Impairment Studies
Share to Retinal Development and Disorders
Share to Retinal Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37099020
DOI: 10.1167/iovs.64.4.32

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Retinal Aging Transcriptome and Cellular Landscape in Association With the Progression of Age-Related Macular DegenerationPMID 37099020Read ↗

Retinal aging transcriptome and cellular landscape in association with the progression of age-related macular degenerationSemantic proximity Read ↗

Age-Related Macular Degeneration: Cellular and Molecular Signaling MechanismsSemantic proximity Read ↗

Integrative single-cell and bulk RNA-seq analysis in human retina identified cell type-specific composition and gene expression changes for age-related macular degenerationSemantic proximity Read ↗

Comparative single-cell multiomic analysis reveals evolutionarily conserved and species-specific cellular mechanisms mediating natural retinal agingSemantic proximity Read ↗

Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration.Semantic proximity Read ↗

Rat retinal transcriptome: Effects of aging and AMD-like retinopathySemantic proximity Read ↗

Implication of specific retinal cell-type involvement and gene expression changes in AMD progression using integrative analysis of single-cell and bulk RNA-seq profilingSemantic proximity Read ↗

Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networksSemantic proximity Read ↗

Interpretable Aging Signatures in Human Retinal Cell Types Revealed by Single-Cell RNA Sequencing and Sparse Logistic RegressionSemantic proximity Read ↗

Molecular Crosstalk in Age-Related Macular Degeneration: Integrating Oxidative Stress, Inflammation, microRNAs, and Genetic Susceptibility Toward Precision Therapeutics.Semantic proximity Read ↗

An Integrated Multi-omics Single Cell Atlas of the Human RPE and ChoroidSemantic proximity Read ↗

A single-cell transcriptome atlas of the aging human and macaque retinaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.