Article

Activation of Protein Kinase R (PKR) Plays a Pro-Viral Role in Mammarenavirus Infected Cells

2023-12-06

Abstract excerpt

<h4>ABSTRACT</h4> Many viruses, including mammarenaviruses, have evolved mechanisms to counteract different components of the host cell innate immunity, which is required to facilitate robust virus multiplication. The double strand (ds)RNA sensor protein kinase receptor (PKR) pathway plays a critical role in the cell antiviral response. Whether PKR can restrict the multiplication of the Old World mammarenavirus l...

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Literature Corpus work: bd489ddc-175c-525e-8040-996ab4858b65
DOI: 10.1101/2023.12.05.570143

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