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Activation of the DNA Damage Response by RNA Viruses

6 Jan 2016

Abstract excerpt

RNA viruses are a genetically diverse group of pathogens that are responsible for some of the most prevalent and lethal human diseases. Numerous viruses introduce DNA damage and genetic instability in host cells during their lifecycles and some species also manipulate components of the DNA damage response (DDR), a complex and sophisticated series of cellular pathways that have evolved to detect and repair DNA...

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PMID: 26751489
DOI: 10.3390/biom6010002

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