Article

Nucleolar stress in <i>Drosophila</i> neuroblasts, a model for human ribosomopathies

2019-07-16

Abstract excerpt

<h4>ABSTRACT</h4> Different stem cells or progenitor cells display variable threshold requirements for functional ribosomes. For instance, select embryonic neural crest cells or adult bone marrow stem cells, but not others, show lethality due to failures in ribosome biogenesis or function (known as nucleolar stress) in several human ribosomopathies. To determine if various Drosophila neuroblasts display differen...

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Literature Corpus work: bd47d04d-821f-5fba-bf11-4ba6b9ee60b4
DOI: 10.1101/704734

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