Article

Copy number evolution in simple and complex tandem repeats across the C57BL/6 and C57BL/10 inbred mouse lines

2021-03-02

Abstract excerpt

Simple sequence tandem repeats are among the most rapidly evolving compartments of the genome. Some repeat expansions are associated with mammalian disease or meiotic segregation distortion, yet the rates of copy number change across generations are not well known. Here, we use 14 distinct sub-lineages of the C57BL/6 and C57BL/10 inbred mouse strains, which have been evolving independently over about 300 generatio...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bd427e2e-60b4-53f7-8f2a-9a10b3c03ac2
DOI: 10.1101/2021.03.01.433487

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Copy number evolution in simple and complex tandem repeats across the C57BL/6 and C57BL/10 inbred mouse linesDOI 10.1101/2021.03.01.433487Read

Recurrent DNA copy number variation in the laboratory mouse.Semantic proximity Read

The rate and spectrum of new mutations in mice inferred by long-read sequencing.Semantic proximity Read

Sequence and structural diversity of mouse Y chromosomesSemantic proximity Read

Inherent instability of simple DNA repeats shapes an evolutionarily stable distribution of repeat lengthsSemantic proximity Read

Mouse segmental duplication and copy number variation.Semantic proximity Read

Length of uninterrupted repeats determines instability at the unstable mouse expanded simple tandem repeat family MMS10 derived from independent SINE B1 elements.Semantic proximity Read

A Tandem Repeat Atlas for the Genome of Inbred Mouse Strains: A Genetic Variation ResourceSemantic proximity Read

Tandem repeat polymorphisms: Mediators of genetic plasticity, modulators of biological diversity and dynamic sources of disease susceptibility.Semantic proximity Read

Divergent genome evolution caused by regional variation in DNA gain and loss between human and mouseSemantic proximity Read

AI Analysis of a Copy Number Variant Database Identifies a Genetic Factor for a Murine Model of the Metabolic SyndromeSemantic proximity Read

Covariation in frequencies of substitution, deletion, transposition, and recombination during eutherian evolution.Semantic proximity Read

Genome-wide mapping and assembly of structural variant breakpoints in the mouse genome.Semantic proximity Read