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Article

Genetic markers associated with dihydroartemisinin-piperaquine failure in Plasmodium falciparum malaria in Cambodia: a genotype-phenotype association study.

The Lancet. Infectious diseases - 1 Feb 2017

Amato Roberto, Lim Pharath, Miotto Olivo, Amaratunga Chanaki, Dek Dalin, Pearson Richard D, Almagro-Garcia Jacob, Neal Aaron T, Sreng Sokunthea, Suon Seila, Drury Eleanor, Jyothi Dushyanth, Stalker Jim, Kwiatkowski Dominic P, Fairhurst Rick M

Abstract excerpt

BACKGROUND: As the prevalence of artemisinin-resistant Plasmodium falciparum malaria increases in the Greater Mekong subregion, emerging resistance to partner drugs in artemisinin combination therapies seriously threatens global efforts to treat and eliminate this disease. Molecular markers that predict failure of artemisinin combination therapy are urgently needed to monitor the spread of partner drug...

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Identifiers

PMID: 27818095
DOI: 10.1016/S1473-3099(16)30409-1
PMCID: PMC5564489

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Source receipt: pubmed, retrieved 7 Sept 2026.

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