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Assessment of polymeric immunoglobulin A and M via detection of the joining chain

2026-07-16

Abstract excerpt

Polymeric immunoglobulin M (IgM) and A (IgA) play key roles in systemic and mucosal immunity, yet quantitative assessment of their polymeric forms has been hampered by the lack of robust, high-throughput assays. Polymerization of both isotypes implies incorporation of the joining chain (J chain), making direct detection of integrated J chain an attractive surrogate marker. Here, we report the generation and charac...

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Literature Corpus work
bd17528f-e1f1-58a8-a321-8c9d3f7f10dc
DOI
10.64898/2026.07.14.737820
Open publication

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Assessment of polymeric immunoglobulin A and M via detection of the joining chainDOI 10.64898/2026.07.14.737820
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