Article

Information That Cannot Be Gained by Studies of Serum Antibodies: ImmunoSpot Assays Permit Detailed Assessment of Antigen-Specific Memory B Cells Through Defining Their Frequency, Affinity, Cross-Reactivity Profile, and Antibody Class/Subclass Utilization

2024-11-27

Abstract excerpt

Determining an individual’s humoral immune reactivity to a pathogen, autoantigen, or environmental agent is traditionally accomplished through assessment of specific antibody levels in blood. However, in many instances, titers of specific antibodies decline over time and thus do not faithfully reveal prior antigen exposure or establishment of immunological memory. To estimate an individual’s humoral immune compete...

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Literature Corpus work: 92fc6b2d-bec6-5cae-87f7-81917a8b5538
DOI: 10.20944/preprints202411.2114.v1

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Information That Cannot Be Gained by Studies of Serum Antibodies: ImmunoSpot Assays Permit Detailed Assessment of Antigen-Specific Memory B Cells Through Defining Their Frequency, Affinity, Cross-Reactivity Profile, and Antibody Class/Subclass UtilizationDOI 10.20944/preprints202411.2114.v1Read

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