Article

A gFET-based Sensor Equipped with a Focused Post-SELEX Aptamer Library for Specific Quantification of the Hormone-like Anti-Aging Protein Klotho in Human Serum

2026-08-25

Abstract excerpt

<title>Abstract</title> <p>The Klotho (KL) gene encodes a single-pass transmembrane protein that functions as a potent suppressor of aging. In humans, reduced Klotho expression is associated with aging, diabetes, Alzheimer’s disease and other age-related disorders, correlating with increased all-cause mortality. The full-length α-Klotho protein consists of two extracellular domains, KL1 and KL2, which are proteol...

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Literature Corpus work: bcf9c8f2-d7ac-5675-8300-979a83628c6a
DOI: 10.21203/rs.3.rs-10661096/v1

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A gFET-based Sensor Equipped with a Focused Post-SELEX Aptamer Library for Specific Quantification of the Hormone-like Anti-Aging Protein Klotho in Human SerumDOI 10.21203/rs.3.rs-10661096/v1Read

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