Article

Aptamers Selected for Recognizing Amyloid β-protein—A Case for Cautious Optimism

2018-02-05

Abstract excerpt

Aptamers are versatile oligonucleotide ligands used for molecular recognition of diverse targets. However, application of aptamers to the field of amyloid β-protein (Aβ) has been limited so far. Aβ is an intrinsically disordered protein that exists in a dynamic conformational equilibrium, presenting time-dependent ensembles of short-lived, metastable structures and assemblies that have been generall...

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Literature Corpus work: 5796e547-f796-5128-8756-0987a059d4f8
DOI: 10.20944/preprints201802.0047.v1

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