Article

The Crohn’s disease-related AIEC strain LF82 assembles a biofilm-like matrix to protect intracellular microcolonies from phagolysosomal attack

2020-03-31

Abstract excerpt

Patients with Crohn’s disease exhibit abnormal colonization of the intestine by proteobacteria, and among these bacteria, the adherent invasive E. coli (AIEC) family. They are predominant in the mucus, adhere to epithelial cells, colonize them and survive inside macrophages. We recently demonstrated that the acclimation of the AIEC strain LF82 to phagolysosomal stress requires stringent and SOS responses. Such ad...

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Literature Corpus work: 0dd9a207-73dd-5275-bff0-32b3fd0020cb
DOI: 10.1101/2020.03.31.014175

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