Article

Microglial MorphOMICs unravel region- and sex-dependent morphological phenotypes from postnatal development to degeneration

2021-12-01

Abstract excerpt

Microglia contribute to tissue homeostasis in physiological conditions with environmental cues influencing their ever-changing morphology. Strategies to identify these changes usually involve user-selected morphometric features, which, however, have proved ineffective in establishing a spectrum of context-dependent morphological phenotypes. Here, we have developed MorphOMICs, a topological data analysis approach t...

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Literature Corpus work: bcd14e8d-ae3e-5db8-98f2-78f38adabb20
DOI: 10.1101/2021.11.30.470610

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