Article

Intrathecal injection of human umbilical cord mesenchymal stem cells genetically engineered to overexpress Heme oxygenase 1 promotes symptoms recovery in cyclophosphamide-induced cystitis rats by alleviating neuroinflammation

2022-07-13

Abstract excerpt

<h4>Background: </h4> Interstitial cystitis/bladder pain syndrome (IC/BPS) seriously affect the patient's quality of life, yet current therapies for IC/BPS only provide partial relief. Neuroinflammation in the spinal dorsal horn (SDH) plays a pivotal role in the pathogenesis. Injection of human umbilical mesenchymal stem cells (hUMSCs) represent an effective strategy to reduce inflammation, and heme oxygenase-1 (H...

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Literature Corpus work: bc900b5e-1c1a-576f-a727-443cec2d9d6d
DOI: 10.21203/rs.3.rs-1747929/v1

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Intrathecal injection of human umbilical cord mesenchymal stem cells genetically engineered to overexpress Heme oxygenase 1 promotes symptoms recovery in cyclophosphamide-induced cystitis rats by alleviating neuroinflammationDOI 10.21203/rs.3.rs-1747929/v1Read

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