Article

TGF-β inhibitor treatment of H₂O₂-induced cystitis models provide molecular mechanism for elucidating interstitial cystitis/painful bladder syndrome patients.

2023-03-15

Abstract excerpt

Interstitial cystitis/painful bladder syndrome (IC/PBS) is a chronic disease for which no effective treatment is available. Transforming growth factor-β (TGF-β) is thought to be involved in the pathogenesis of IC/PBS, and previous studies have suggested that administrations of a TGF-β inhibitor significantly ameliorated IC/PBS in a mouse model. However, the molecular mechanisms underlying the therapeutic effect of...

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Literature Corpus work: 8028e50f-34c3-5896-8f9c-ba8beadcc5fa
DOI: 10.21203/rs.3.rs-2611246/v1

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