Article

A SUMO E3 ligase promotes long non-coding RNA transcription to regulate small RNA-directed DNA elimination

2023-09-27

Abstract excerpt

Small RNAs target their complementary chromatin regions for gene silencing through nascent long non-coding RNAs (lncRNAs). In the ciliated protozoan Tetrahymena , the interaction between Piwi-associated small RNAs (scnRNAs) and the nascent lncRNA transcripts from the somatic genome has been proposed to induce target-directed small RNA degradation (TDSD), and scnRNAs not targeted for TDSD later target the germline...

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Literature Corpus work: bc824ae1-6937-5949-952d-f7863495b2e8
DOI: 10.1101/2023.09.27.558415

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