Article

Genome-wide differential expression profiling of long non-coding RNAs in FOXA2 knockout iPSC-derived pancreatic cells

2023-04-18

Abstract excerpt

<h4>Background: </h4> Our recent studies have demonstrated the crucial involvement of FOXA2 in the development of human pancreas. Reduction of FOXA2 expression during the differentiation of induced pluripotent stem cells (iPSCs) into pancreatic islets has been found to reduce α -and β-cell masses. However, the extent to which such changes are linked to alterations in the expression profile of long non-coding RNAs...

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Literature Corpus work: bc79032c-e2c1-5466-8457-cf51e2880dcb
DOI: 10.21203/rs.3.rs-2812417/v1

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