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Article

Transcriptome analysis of pancreatic cells across distant species highlights novel important regulator genes.

BMC biology - 21 Mar 2017

Tarifeño-Saldivia Estefania, Lavergne Arnaud, Bernard Alice, Padamata Keerthana, Bergemann David, Voz Marianne L, Manfroid Isabelle, Peers Bernard

Abstract excerpt

BACKGROUND: Defining the transcriptome and the genetic pathways of pancreatic cells is of great interest for elucidating the molecular attributes of pancreas disorders such as diabetes and cancer. As the function of the different pancreatic cell types has been maintained during vertebrate evolution, the comparison of their transcriptomes across distant vertebrate species is a means to pinpoint genes under strong...

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Identifiers

PMID: 28327131
DOI: 10.1186/s12915-017-0362-x
PMCID: PMC5360028

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