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Cerebrospinal fluid inflammome analysis identifies host- and pathogen-specific inflammatory profiles and signaling pathways in meningitis and predicts clinical outcome

2025-03-30

Abstract excerpt

Increasing evidence indicate that individual host immune response to pathogens may be as important as virulence factors in determining the severity of infection. However, most available data on pathogen-host interactions are based on in vitro findings, neglecting the genetic complexity of the immune response. We conducted a comparative observational study of bacterial and viral meningitis to identify pathogen-spec...

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Literature Corpus work
bc39c64f-b87a-5c02-b4d8-d5f25b19413b
DOI
10.1101/2025.03.27.645675
Open publication

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Cerebrospinal fluid inflammome analysis identifies host- and pathogen-specific inflammatory profiles and signaling pathways in meningitis and predicts clinical outcomeDOI 10.1101/2025.03.27.645675
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