Article

Could ozone become a complementary therapeutic approach to improve metabolic and endocrine response of ALS patients?

2022-05-03

Abstract excerpt

Amyotrophic lateral sclerosis (ALS), a devastating progressive neurodegenerative disease, has no effective treatment. Recent evidence supports a strong metabolic component in ALS pathogenesis, raising additional therapeutic targets against ALS. At this respect, improvements in motor deficits and disease-associated weight loss after repeated exposures to ozone (O 3 ) in the mouse model of ALS based on TDP-43 protei...

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Literature Corpus work: bc322697-8197-505b-94df-db4a0e7bda9e
DOI: 10.21203/rs.3.rs-1616097/v1

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