Article

Early transcriptional landscapes of <i>Chlamydia trachomatis</i> -infected epithelial cells at single cell resolution

2019-08-05

Abstract excerpt

Chlamydia are Gram-negative obligate intracellular bacterial pathogens responsible for a variety of disease in humans and animals worldwide. C. trachomatis causes trachoma (infectious blindness) in disadvantaged populations, and is the most common bacterial sexually transmitted infection in humans, causing reproductive tract disease. Antibiotic therapy successfully treats diagnosed chlamydial infections, however...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bbe48d0e-b87a-5201-b1f8-391c0e39ab3a
DOI: 10.1101/724641

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Early transcriptional landscapes of <i>Chlamydia trachomatis</i> -infected epithelial cells at single cell resolutionDOI 10.1101/724641Read

Simultaneous Transcriptional Profiling of Bacteria and Their Host CellsSemantic proximity Read

Host cell response and distinct gene expression profiles at different stages of Chlamydia trachomatis infection reveals stage-specific biomarkers of infectionSemantic proximity Read

Comparative transcriptomic profiling of human conjunctival epithelial cells and macrophages in response to <i>Chlamydia trachomatis</i> genovars A and B in early- and mid-infection cyclesSemantic proximity Read

The T3SS structural and effector genes of <i>Chlamydia trachomatis</i> are expressed in distinct phenotypic cell formsSemantic proximity Read

Single-cell atlas of patient-derived cervical organoids uncovers epithelial immune heterogeneity and intercellular crosstalk during Chlamydia infectionSemantic proximity Read

Chromatin accessibility dynamics of <i>Chlamydia</i> -infected epithelial cellsSemantic proximity Read

Chlamydia trachomatisInfection Alters Host Cell Transcription in Diverse Cellular PathwaysSemantic proximity Read

Host cell amplification of nutritional stress contributes to persistence in <i>Chlamydia trachomatis</i>Semantic proximity Read

Identification of the alternative sigma factor regulons of <i>Chlamydia trachomatis</i> using multiplexed CRISPR interferenceSemantic proximity Read

Euo is a developmental regulator that represses late genes and activates midcycle genes in Chlamydia trachomatisSemantic proximity Read

ORIGINAL ARTICLE: A Distinct Cellular Profile Is Seen in the Human Endocervix During Chlamydia trachomatis InfectionSemantic proximity Read

Cell Type Development in <i>Chlamydia trachomatis</i> Follows a Program Intrinsic to the Reticulate BodySemantic proximity Read