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Chlamydia trachomatisInfection Alters Host Cell Transcription in Diverse Cellular Pathways

1 Feb 2003

Abstract excerpt

To study the responses of the host cell to chlamydial infection, differentially transcribed genes of the host cells were examined. Complementary DNA (cDNA) probes were made from messenger RNAs of HeLa cells infected with Chlamydia trachomatis and were hybridized to a high-density human DNA microarray of 15,000 genes and expressed sequence tags. C. trachomatis alters host cell transcription at both the early and...

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PMID: 12552426
DOI: 10.1086/367962

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