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Identification of the alternative sigma factor regulons of <i>Chlamydia trachomatis</i> using multiplexed CRISPR interference

2023-04-28

Abstract excerpt

C. trachomatis is a developmentally regulated, obligate intracellular bacterium that encodes three sigma factors: σ66, σ54, and σ28. σ66 is the major sigma factor controlling most transcription initiation during early and mid-cycle development as the infectious EB transitions to the non-infectious RB that replicates within an inclusion inside the cell. The roles of the minor sigma factors, σ54 and σ28, have not be...

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Literature Corpus work
94de64a6-cf35-58d0-acd6-0dfbef6aa8e9
DOI
10.1101/2023.04.27.538638
Open publication

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Identification of the alternative sigma factor regulons of <i>Chlamydia trachomatis</i> using multiplexed CRISPR interferenceDOI 10.1101/2023.04.27.538638
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