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Comparative transcriptomic profiling of human conjunctival epithelial cells and macrophages in response to <i>Chlamydia trachomatis</i> genovars A and B in early- and mid-infection cycles

2025-11-24

Abstract excerpt

Chlamydia trachomatis (Ct), an obligate intracellular bacterium, is the primary infectious cause of blindness through trachoma. Ct undergoes a unique biphasic developmental cycle between infectious elementary bodies and replicating reticulate bodies, manipulating host cells via secreted effector proteins. Whilst previous studies have characterised host-pathogen interactions including transcriptomes of urogenital C...

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Literature Corpus work
ceb88b7c-1930-595c-8f59-fe86a708a439
DOI
10.1101/2025.11.24.689971
Open publication

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Comparative transcriptomic profiling of human conjunctival epithelial cells and macrophages in response to <i>Chlamydia trachomatis</i> genovars A and B in early- and mid-infection cyclesDOI 10.1101/2025.11.24.689971
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