Article
The Assessment of Selected miRNA Profile in Familial Mediterranean Fever.
BioMed research international - 1 Jan 2021
Kahraman Cigdem Yuce, Egin Mehmet Ertugrul, Tatar Abdulgani, Turkez Hasan, Mardinoglu Adil
Abstract excerpt
Familial Mediterranean fever (FMF) is the most prevalent autoinflammatory disease. Typical findings are recurrent fever attacks with serositis, skin rash, and synovitis. FMF is caused by mutations in the MEFV gene, encoding pyrin protein. Pyrin functions in innate immunity and triggers inflammation via inflammatory mediators' production and acts as the primary regulatory component of the inflammasome. On the...
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