Article

Genome-wide classification of tumor-derived reads from bulk long-read sequencing

2026-03-05

Abstract excerpt

DNA extracted from tissue samples typically derives from a complex mixture of cell types. Without single cell analysis, it has been generally impossible to determine the cell type of origin for most molecules. One clear example of this is in the complex milieu of a human neoplasm. Here, we develop ROCIT ( https://github.com/tobybaker/rocit ), a transformer-based model to classify the tumor or non-tumor origin of...

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Literature Corpus work: bbb91a83-b8b4-5cf5-8929-02c9f329fb0f
DOI: 10.64898/2026.03.03.709085

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