Back to search

Article

The adequacy of tissue microarrays in the assessment of inter- and intra-tumoural heterogeneity of infiltrating lymphocyte burden in leiomyosarcoma

2018-09-10

Abstract excerpt

The characterisation and clinical relevance of tumour-infiltrating lymphocytes (TILs) in leiomyosarcoma (LMS), a subtype of soft tissue sarcoma that exhibits histological heterogeneity, is not established. The use of tissue microarrays (TMA) in studies that profile TIL burden is attractive but given the potential for intra-tumoural heterogeneity to introduce sampling errors, the adequacy of this approach is undete...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
bbaee5c0-25f6-55c4-a1ec-88490e090e7a
DOI
10.1101/412387
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 10 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The adequacy of tissue microarrays in the assessment of inter- and intra-tumoural heterogeneity of infiltrating lymphocyte burden in leiomyosarcomaDOI 10.1101/412387
The adequacy of tissue microarrays in the assessment of inter- and intra-tumoural heterogeneity of infiltrating lymphocyte burden in leiomyosarcomaSemantic proximity
The proteomic landscape of soft tissue sarcomasSemantic proximity
PD-L1 expression in 522 selected sarcomas with subset analysis of recurrent or metastatic matched samples and association with tumour-infiltrating lymphocytesSemantic proximity
Clinical Implications and Molecular Features of Extracellular Matrix Networks in Soft Tissue SarcomasSemantic proximity
Prognostic attributes of immune signatures in soft tissue sarcomas show differential dependencies on tumor mutational burden.Semantic proximity
High Quality Genomic Copy Number Data from Archival Formalin-Fixed Paraffin-Embedded Leiomyosarcoma: Optimisation of Universal Linkage System LabellingSemantic proximity
Measured intrapatient radiomic variability as a predictor of treatment response in multi-metastatic soft tissue sarcoma patientsSemantic proximity
Gene copy number profiling of soft-tissue leiomyosarcomas by array-comparative genomic hybridizationSemantic proximity
YAP and collagen remodelling support cell proliferation and tumour aggressiveness in uterine leiomyosarcomaSemantic proximity
Telomere Maintenance Mechanisms in Liposarcomas: Association with Histologic Subtypes and Disease ProgressionSemantic proximity
Select a neighboring publication to make it the new centre.