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Article

The proteomic landscape of soft tissue sarcomas

29 Jun 2023

Abstract excerpt

Soft tissue sarcomas (STS) are rare and diverse mesenchymal cancers with limited treatment options. Here we undertake comprehensive proteomic profiling of tumour specimens from 321 STS patients representing 11 histological subtypes. Within leiomyosarcomas, we identify three proteomic subtypes with distinct myogenesis and immune features, anatomical site distribution and survival outcomes. Characterisation of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37386008
DOI: 10.1038/s41467-023-39486-2

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