Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High Quality Genomic Copy Number Data from Archival Formalin-Fixed Paraffin-Embedded Leiomyosarcoma: Optimisation of Universal Linkage System Labelling

29 Nov 2012

Abstract excerpt

Most soft tissue sarcomas are characterized by genetic instability and frequent genomic copy number aberrations that are not subtype-specific. Oligonucleotide microarray-based Comparative Genomic Hybridisation (array CGH) is an important technique used to map genome-wide copy number aberrations, but the traditional requirement for high-quality DNA typically obtained from fresh tissue has limited its use in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Molecular Biology Techniques and Applications
Share to Sarcoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23209738
DOI: 10.1371/journal.pone.0050415

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High Quality Genomic Copy Number Data from Archival Formalin-Fixed Paraffin-Embedded Leiomyosarcoma: Optimisation of Universal Linkage System LabellingPMID 23209738Read ↗

DNA Copy Number Changes in Development and Progression in Leiomyosarcomas of Soft TissuesSemantic proximity Read ↗

Integrative genomic and transcriptomic analysis of leiomyosarcoma.Semantic proximity Read ↗

Leiomyosarcomas and Most Malignant Fibrous Histiocytomas Share Very Similar Comparative Genomic Hybridization Imbalances: An Analysis of a Series of 27 LeiomyosarcomasSemantic proximity Read ↗

Gene copy number profiling of soft-tissue leiomyosarcomas by array-comparative genomic hybridizationSemantic proximity Read ↗

Dual Probe Ligation In Situ Hybridization with Rolling-Circle Amplification for High-Plex Spatial TranscriptomicsSemantic proximity Read ↗

Structural variation detection by proximity ligation from FFPE tumor tissueSemantic proximity Read ↗

Detection of chromosomal imbalances in leiomyosarcoma by comparative genomic hybridization and interphase cytogeneticsSemantic proximity Read ↗

Detection of Circulating Tumor DNA in Patients With Leiomyosarcoma With Progressive DiseaseSemantic proximity Read ↗

Genomic characterization and histologic analysis of uterine leiomyosarcoma arising from leiomyoma with bizarre nucleiSemantic proximity Read ↗

Using next-generation sequencing for high resolution multiplex analysis of copy number variation from nanogram quantities of DNA from formalin-fixed paraffin-embedded specimensSemantic proximity Read ↗

Odontogenic Myxomas Harbor Recurrent Copy Number Alterations and a Distinct Methylation SignatureSemantic proximity Read ↗

Random DNA fragmentation allows detection of single-copy, single-exon alterations of copy number by oligonucleotide array CGH in clinical FFPE samplesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.