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Article

Prognostic attributes of immune signatures in soft tissue sarcomas show differential dependencies on tumor mutational burden.

Cancer - 1 Sept 2022

Raj Shailaja K S, Routh Eric D, Chou Jeff W, Votanopoulos Konstantinos I, Triozzi Pierre L, Miller Lance D

Abstract excerpt

BACKGROUND: Cellular and intrinsic markers of sarcoma immunogenicity are poorly understood. To gain insight into whether tumor-immune interactions correlate with clinical aggressiveness, the authors examined the prognostic significance of immune gene signatures in combination with tumor mutational burden (TMB) and cancer-testis antigen (CTA) expression. METHODS: RNA sequencing and clinical data of 259 soft tissue...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35767280
DOI: 10.1002/cncr.34333
PMCID: PMC9544607

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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