Article

Altered Bile Acid Profile Associates with Cognitive Impairment in Alzheimer’s Disease – An Emerging Role for Gut Microbiome

2018-03-17

Abstract excerpt

<h4>Introduction</h4> Increasing evidence suggests a role for the gut microbiome in central nervous system disorders and specific role for the gut-brain axis in neurodegeneration. Bile acids (BA), products of cholesterol metabolism and clearance, are produced in the liver and are further metabolized by gut bacteria. They have major regulatory and signaling functions and seem dysregulated in Alzheimer disease (AD)...

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Literature Corpus work: bb85b411-0db7-522d-81c9-a5c894ca0415
DOI: 10.1101/281956

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