Article

The Gut-Brain Axis in Alzheimer’s Disease: Microbiota as a Key Contributor to Disease Pathogenesis

2026-08-31

Abstract excerpt

Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder influenced by genetic, environmental, and lifestyle factors. Increasing evidence indicates that the gut microbiota composition is a key modulator of AD pathogenesis, driving neuroinflammation, and amyloid and tau pathology through the microbiota–gut–brain axis. This review synthesizes current findings on the mechanistic pathways by which alter...

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Literature Corpus work: 230c12a7-e6f9-5912-abf7-642f1639c7d1
DOI: 10.20944/preprints202608.2280.v1

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