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<i>Hoslundia opposita</i> and other Nigerian plants inhibit sickle hemoglobin polymerization and prevent erythrocyte sickling: a virtual screening-guided identification of bioactive plants

2021-07-26

Abstract excerpt

In sickle cell disease, a hereditary hemoglobinopathy, clinically observed disease presentations are the endpoint of a point mutation involving the substitution of glutamic acid with valine at the position 6 of the beta globin chain. With about 4.4 million people globally being affected, and another 43 million people bearing the sickle cell trait, several research efforts have been made to discover new and afforda...

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Literature Corpus work
bb48b979-6203-5f33-8efc-c82b672744a1
DOI
10.1101/2021.07.25.453693
Open publication

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<i>Hoslundia opposita</i> and other Nigerian plants inhibit sickle hemoglobin polymerization and prevent erythrocyte sickling: a virtual screening-guided identification of bioactive plantsDOI 10.1101/2021.07.25.453693
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