Article

In Silico Post-screening of Anti-polymerization Agents to Treat Sickle Cell Disease

2025-10-26

Abstract excerpt

Sickle cell disease (SCD) is a genetic disorder that affects approximately 100,000 individuals in the United States and millions globally. Although curative therapies, such as stem cell transplant and gene therapy, are available, their application is limited by high cost and donor availability. Consequently, drug therapy remains the most feasible treatment option for the majority of patients with SCD. To date, onl...

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Literature Corpus work: 6f06a4b5-5642-589a-bfc8-ca2778b8db04
DOI: 10.1101/2025.10.25.684554

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