Article

Isolation and characterisation of quercitrin as a potent anti-sickle cell anaemia agent from <i>Alchornea cordifolia</i>

2021-11-23

Abstract excerpt

Alchornea cordifolia Müll. Arg. (commonly known as Christmas Bush) has been used traditionally in Africa to treat sickle cell anaemia (a recessive disease, arising from the S haemoglobin [Hb] allele) but the active compounds are yet to be characterised. Herein we describe the use of sequential fractionation coupled with in vitro anti-sickling assays to purify the active component. Sickling was induced in Hb SS...

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Literature Corpus work: bb6b9737-3e6b-5398-b439-39d0a0052f1a
DOI: 10.1101/2021.11.11.468287

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