Article

Phenotypic screening of the ReFrame Drug Repurposing Library to discover new drugs for treating sickle cell disease

2022-06-26

Abstract excerpt

Stem-cell transplantation and genetic therapies offer potential cures for patients with sickle cell disease (SCD) but these options require advanced medical facilities and are expensive. Consequently, these treatments will not be available to the vast majority of patients suffering from this disease for many years. What is urgently needed now is an inexpensive oral drug in addition to hydroxyurea, the only success...

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Literature Corpus work: 7fcd76a6-9634-592c-9268-a20b3beb196d
DOI: 10.1101/2022.06.23.497377

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