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Article

Phytomedicines and Nutraceuticals: Alternative Therapeutics for Sickle Cell Anemia

1 Jan 2013

Abstract excerpt

Sickle cell anemia is a genetically inherited disease in which the "SS" individual possesses an abnormal beta globin gene. A single base substitution in the gene encoding the human β -globin subunit results in replacement of β 6 glutamic acid by valine, leading to the devastating clinical manifestations of sickle cell disease. This substitution causes drastic reduction in the solubility of sickle cell hemoglobin...

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PMID: 23476125
DOI: 10.1155/2013/269659

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